Tech News
Study: Planned budget cuts would hurt drug development badly
Science - Posted On:2025-09-25 15:00:01 Source: arstechnica
The proposed federal budget would see drastic cuts made to most of the agencies that fund science. The sheer magnitude of the cuts—including a 40 percent slashing of money going to the National Institutes of Health—would do severe harm to biomedical researchers and the industries that serve or rely on them. And, ultimately, that is likely to do harm to all of us.
In today's issue of Science, some researchers have attempted to put numbers on those indirect effects that fall within that "ultimately" category. They've identified which grants wouldn't have been funded had similar cuts been made earlier in this century and tracked the impact that likely had on drug patents. Their conclusion: Development of roughly half the newly approved drugs relied on work that was funded by a grant that would need to be cut.
It's uncertain whether the proposed budget cuts will go through. At the moment, Congress is looking to fund most science agencies at levels similar to their current budgets. Should cuts eventually happen, then it's also difficult to predict how they'll be spread among the more than 20 institutes that make up the NIH (a number that the administration also wants to see reduced via consolidation). So, the researchers make a big simplifying assumption: Every institute within the NIH will take a 40 percent hit to its budget.
Experimental Gene Therapy Found To Slow Huntington's Disease Progression
science - Posted On:2025-09-25 03:15:00 Source: slashdot
Doctors report the first successful treatment for Huntington's disease using a new type of gene therapy given during 12 to 18 hours of delicate brain surgery. The BBC reports: An emotional research team became tearful as they described how data shows the disease was slowed by 75% in patients. It means the decline you would normally expect in one year would take four years after treatment, giving patients decades of "good quality life", Prof Sarah Tabrizi told BBC News. The first symptoms of Huntington's disease tend to appear in your 30s or 40s and is normally fatal within two decades -- opening the possibility that earlier treatment could prevent symptoms from ever emerging. None of the patients who have been treated are being identified, but one was medically retired and has returned to work. Others in the trial are still walking despite being expected to need a wheelchair. Treatment is likely to be very expensive. However, this is a moment of real hope in a disease that hits people in their prime and devastates families. [...] It starts with a safe virus that has been altered to contain a specially designed sequence of DNA. This is infused deep into the brain using real-time MRI scanning to guide a microcatheter to two brain regions - the caudate nucleus and the putamen. This takes 12 to 18 hours of neurosurgery. The virus then acts like a microscopic postman -- delivering the new piece of DNA inside brain cells, where it becomes active. This turns the neurons into a factory for making the therapy to avert their own death. The cells produce a small fragment of genetic material (called microRNA) that is designed to intercept and disable the instructions (called messenger RNA) being sent from the cells' DNA for building mutant huntingtin. This results in lower levels of mutant huntingtin in the brain. [...] The data showed that three years after surgery there was an average 75% slowing of the disease based on a measure which combines cognition, motor function and the ability to manage in daily life. The data also shows the treatment is saving brain cells. Levels of neurofilaments in spinal fluid -- a clear sign of brain cells dying -- should have increased by a third if the disease continued to progress, but was actually lower than at the start of the trial. Read more of this story at Slashdot.
A “cosmic carpool” is traveling to a distant space weather observation post
Science - Posted On:2025-09-24 15:15:00 Source: arstechnica
Scientists loaded three missions worth nearly $1.6 billion on a SpaceX Falcon 9 rocket for launch Wednesday, toward an orbit nearly a million miles from Earth, to measure the supersonic stream of charged particles emanating from the Sun.
One of the missions, from the National Oceanic and Atmospheric Administration (NOAA), will beam back real-time observations of the solar wind to provide advance warning of geomagnetic storms that could affect power grids, radio communications, GPS navigation, air travel, and satellite operations.
The other two missions come from NASA, with research objectives that include studying the boundary between the Solar System and interstellar space and observing the rarely seen outermost layer of our own planet's atmosphere.
Journals Infiltrated With 'Copycat' Papers That Can Be Written By AI
science - Posted On:2025-09-23 16:15:00 Source: slashdot
An analysis of a literature database finds that text-generating AI tools -- including ChatGPT and Gemini -- can be used to rewrite scientific papers and produce 'copycat' versions that are then passed off as new research. Nature: In a preprint posted on medRxiv on 12 September, researchers identified more than 400 such papers published in 112 journals over the past 4.5 years, and demonstrated that AI-generated biomedicine studies could evade publishers' anti-plagiarism checks. The study's authors warn that individuals and paper mills -- companies that produce fake papers to order and sell authorships -- might be exploiting publicly available health data sets and using large language models (LLMs) to mass-produce low-quality papers that lack scientific value. "If left unaddressed, this AI-based approach can be applied to all sorts of open-access databases, generating far more papers than anyone can imagine," says Csaba Szabo, a pharmacologist at the University of Fribourg in Switzerland, who was not involved in the work. "This could open up Pandora's box [and] the literature may be flooded with synthetic papers." Read more of this story at Slashdot.
Judge lets construction on an offshore wind farm resume
Science - Posted On:2025-09-23 13:30:01 Source: arstechnica
On Monday, a judge blocked the Trump Administration's latest attempt to stifle the US's nascent offshore wind industry. The ruling allows construction to restart on Revolution Wind, which the Danish company Orsted is building in the waters off Rhode Island and Connecticut. While the preliminary injunction can still be appealed, the project is already 80 percent complete, so construction could potentially wrap up while the case is still pending.
The Trump Administration has made no secret of its animosity toward renewable power and issued early executive orders that blocked further offshore leases and re-evaluated the permitting process for others. But it has also gone beyond that and issued stop-work orders for sites that had already been through the permitting process and were under construction. Its reasons for doing so have been remarkably vague, with suggestions of unspecified flaws to the permitting process that involve everything from environmental impacts to detail-free national security concerns.
But those reasons could apparently be ignored under the right circumstances. After blocking further construction of New York's Empire Wind, the administration lifted the block without bothering to explain why its supposed reasons for instituting it no longer applied.
Scientists catch a shark threesome on camera
Science - Posted On:2025-09-23 13:30:00 Source: arstechnica
It's a rare occurrence for scientists to witness sharks mating in the wild. It's even rarer to catch three leopard sharks—two males and one female—engaging in what amounts to a threesome in the wild on camera, particularly since they are considered an endangered species. But that's just what one enterprising marine biology team achieved, describing the mating sequence in careful, clinical detail in a paper published in the Journal of Ethology.
It's not like scientists don't know anything about leopard shark mating behavior; rather, most of that knowledge comes from studying the sharks in captivity. Whether the behavior is identical in the wild is an open question because there hadn't been any documented observations of leopard shark mating practices in the wild—until now.
Hugo Lassauce, a postdoctoral researcher at the University of the Sunshine Coast (UniSC) in Australia, was working with the Aquarium des Lagons in Nouméa, New Caledonia, to monitor sharks off the coast of that South Pacific territory. Lassauce has been snorkeling daily with sharks for a year as part of that program—always with an accompanying boat for safety purposes—and had seen bits of the leopard shark mating behavior before, but never the entire sequence. Then he spotted a female shark on the sand below with two males hanging onto her pectoral fins—classic pre-copulation (courtship) behavior observed in captive leopard sharks.
The Moon is Rusting - Thanks To 'Wind' Blown All the Way From Earth
science - Posted On:2025-09-22 20:00:00 Source: slashdot
The Moon is rusting -- and it's Earth's fault. Nature: Scientists have found that oxygen particles blown from Earth to the Moon can turn lunar minerals into hematite, also known as rust. The discovery adds to researchers' growing understanding of the deep interconnection between Earth and the Moon -- and shows how the Moon keeps a geological record of those interactions, says Ziliang Jin, a planetary scientist at Macau University of Science and Technology in China. He and his colleagues reported their findings earlier this month in Geophysical Research Letters. Most of the time, both Earth and the Moon are bathed in a stream of charged particles emanating from the Sun. But for around five days each month, Earth passes between the Sun and the Moon, blocking most of the flood of solar particles. During that time, the Moon is exposed mainly to particles that had been part of Earth's atmosphere before blowing into space -- a phenomenon known as Earth wind. That wind contains ions of various elements, including hydrogen, oxygen and nitrogen. When those charged particles hit the Moon, they can implant themselves into the upper layers of lunar soil and trigger chemical reactions. Read more of this story at Slashdot.
What climate targets? Top fossil fuel producing nations keep boosting output
Science - Posted On:2025-09-22 10:15:01 Source: arstechnica
The last two years have witnessed the hottest one in history, some of the worst wildfire seasons across Canada, Europe and South America and deadly flooding and heat waves throughout the globe. Over that same period, the world’s largest fossil fuel producers have expanded their planned output for the future, setting humanity on an even more dangerous path into a warmer climate.
Governments now expect to produce more than twice as much coal, oil and gas in 2030 as would be consistent with the goals of the Paris Agreement, according to a report released Monday. That level is slightly higher than what it was in 2023, the last time the biennial Production Gap report was published.
The increase is driven by a slower projected phaseout of coal and higher outlook for gas production by some of the top producers, including China and the United States.
Astronomers Discover Previously Unknown Quasi-Moon Near Earth
science - Posted On:2025-09-21 20:45:00 Source: slashdot
"Astronomers have spotted a quasi-moon near Earth," reports CNN, "and the small space rock has likely been hanging out near our planet unseen by telescopes for about 60 years, according to new research." The newly discovered celestial object, named 2025 PN7, is a type of near-Earth asteroid that orbits the sun but sticks close to our planet. Like our world, 2025 PN7 takes one year to complete an orbit around the sun... The newly found 2025 PN7 is just one of a handful of known quasi-moons with orbits near our planet, including Kamo'oalewa, which is also thought to be an ancient lunar fragment. Kamo'oalewa is one of the destinations of China's Tianwen-2 mission launched in May, which aims to collect and return samples from the space rock in 2027. The Pan-STARRS observatory located on the Haleakala volcano in Hawaii captured observations of 2025 PN7 on August 29. Archival data revealed that the object has been in an Earth-like orbit for decades. The quasi-moon managed to escape the notice of astronomers for so long because it is small and faint, said Carlos de la Fuente Marcos, a researcher on the faculty of mathematical sciences at the Complutense University of Madrid who recently authored a paper about the space rock. The paper was published on September 2 in the journal Research Notes of the American Astronomical Society, which is for timely non-peer-reviewed astronomical observations. The space rock swings within 186,000 miles (299,337 kilometers) of us during its closest pass of our planet, de la Fuente Marcos said.... "It can only be detected by currently available telescopes when it gets close to our planet as it did this summer," de la Fuente Marcos explained. "Its visibility windows are few and far between. It is a challenging object...." Astronomers are still trying to figure out 2025 PN7's size. About 98 feet (30 meters) across is a reasonable estimate, de la Fuente Marcos said. It also has the potential to be 62 feet (19 meters) in diameter, according to EarthSky. The space rock is currently the smallest-known quasi-moon to have orbited near Earth, de la Fuente Marcos said. Read more of this story at Slashdot.
Interlune Signs $300M Deal to Harvest Helium-3 for Quantum Computing from the Moon
science - Posted On:2025-09-20 19:45:00 Source: slashdot
An anonymous reader shared this report from the Washington Post: Finnish tech firm Bluefors, a maker of ultracold refrigerator systems critical for quantum computing, has purchased tens of thousands of liters of Helium-3 from the moon — spending "above $300 million" — through a commercial space company called Interlune. The agreement, which has not been previously reported, marks the largest purchase of a natural resource from space. Interlune, a company founded by former executives from Blue Origin and an Apollo astronaut, has faced skepticism about its mission to become the first entity to mine the moon (which is legal thanks to a 2015 law that grants U.S. space companies the rights to mine on celestial bodies). But advances in its harvesting technology and the materialization of commercial agreements are gradually making this undertaking sound less like science fiction. Bluefors is the third customer to sign up, with an order of up to 10,000 liters of Helium-3 annually for delivery between 2028 and 2037... Helium-3 is lighter than the Helium-4 gas featured at birthday parties. It's also much rarer on Earth. But moon rock samples from the Apollo days hint at its abundance there. Interlune has placed the market value at $20 million per kilogram (about 7,500 liters). "It's the only resource in the universe that's priced high enough to warrant going out to space today and bringing it back to Earth," said Rob Meyerson [CEO of Interlune and former president of Blue Origin]... [H]eat, even in small doses, can cause qubits to produce errors. That's where Helium-3 comes in. Bluefors makes the cooling technology that allows the computer to operate — producing chandelier-type structures known as dilution refrigerators. Their fridges, used by quantum computer leader IBM, contain a mixture of Helium-3 and Helium-4 that pushes temperatures below 10 millikelvins (or minus-460 degrees Fahrenheit)... Existing quantum computers have been built with more than a thousand qubits, he said, but a commercial system or data center would need a million or more. That could require perhaps thousands of liters of Helium-3 per quantum computer. "They will need more Helium-3 than is available on planet Earth," said Gary Lai [a co-founder and chief technology officer of Interlune, who was previously the chief architect at Blue Origin]. Most Helium-3 on Earth, he said, comes from the decay of tritium (an isotope of hydrogen) in nuclear weapons stockpiles, but between 22,000 and 30,000 liters are made each year... "We estimate there's more than a million metric tons of Helium-3 on the moon," Meyerson said. "And it's been accumulating there for 4 billion years." Now, they just need to get it. Interlune CEO Meyerson tells the post "It's really all about establishing a resilient supply chain for this critical material" — adding that in the long-term he could also see Helium-3 being used for other purposes including fusion energy. Read more of this story at Slashdot.
Doomed 'Cannibal' Star Could Explode In a Supernova Visible During Day
science - Posted On:2025-09-20 16:00:00 Source: slashdot
"Betelgeuse may have competition for the most exciting star about to go nova near Earth," writes Space.com. "Astronomers have discovered the secret of a strange star system that has baffled them for years, finding it contains a dead star about to erupt after overfeeding on a stellar companion." The supernova explosion of this cosmic cannibal could be as bright as the moon, making it visible with the naked eye over Earth even in broad daylight. The system in question is the double star V Sagittae located around 10,000 light-years from Earth, containing a white dwarf stellar remnant and its victim companion star, which orbit each other roughly twice every Earth day. The new research and the revelation of this white dwarf's imminent catastrophic fate answer questions about V Sagittae that have lingered for 123 years... White dwarfs represent the final stage of stars with masses around that of the sun, occurring when they run out of fuel for nuclear fusion... [W]hite dwarfs that have a stellar companion can get a second lease on life and a more conclusive and explosive end... [T]he stolen stellar material piles up on the surface of the white dwarf until it pushes this stellar remnant past the so-called Chandrasekhar limit of 1.4 solar masses. This is the mass limit that a stellar remnant has to exceed to trigger a supernova... However, this team found something very different and extraordinary happening with the stellar material being stolen by the white dwarf in V Sagittae... This investigation revealed that there is a giant halo of gas comprised of material stolen from the companion star wrapped around both the cannibal white dwarf and its stellar victim... "The white dwarf cannot consume all the mass being transferred from its hot star twin, so it creates this bright cosmic ring," team member Pasi Hakala from the University of Turku said. "The speed at which this doomed stellar system is lurching wildly, likely due to the extreme brightness, is a frantic sign of its imminent, violent end." "The matter accumulating on the white dwarf is likely to produce a nova outburst in the coming years, during which V Sagittae would become visible with the naked eye," Pablo Rodr�guez-Gil from Spain's Instituto de Astrofisica de Canarias said. "But when the two stars finally smash into each other and explode, this would be a supernova explosion so bright it'll be visible from Earth even in the daytime." The research was conducted with the Very Large Telescope (four individual telescopes high in the mountains of Chile) — and published last week in the journal Monthly Notices of the Royal Astronomical Society. Read more of this story at Slashdot.
Study Links Microplastic Exposure to Alzheimer's Disease in Mice
science - Posted On:2025-09-20 14:15:00 Source: slashdot
Micro- and nanoplastic particles "infiltrate all systems of the body, including the brain," notes the University of Rhode Island, "where they can accumulate and trigger Alzheimer's-like conditions, according to a new study by researchers in the University of Rhode Island College of Pharmacy." ScienceDaily shares the announcement: After a previous study that showed how microplastics can infiltrate all systems of the body — including the blood-brain barrier, which protects the brain from harmful substances as small as viruses and bacteria — University of Rhode Island pharmacy assistant professor Jaime Ross expanded the study to determine the brain health impacts of the plastic toxins. Her findings indicate that the accumulation of micro- and nanoplastics in the brain can lead to cognitive decline and even Alzheimer's disease, especially in those who carry genetic risk factors. Ross' latest study, published recently in the journal Environmental Research Communications, examined mice that had been genetically modified to include the naturally occurring gene APOE4, a strong indicator of Alzheimer's risk making people 3.5 times more likely to develop the disease than those who carry the APOE3 variant of the gene that is passed from parents to offspring... Ross and her team exposed two groups of mice — one with the APOE4 variant and one with APOE3 — to micro- and nanoplastics in their drinking water over a period of three weeks. The tiny particles from polystyrene — among the most abundant plastics in the world, found in Styrofoam take-out containers, plastic cups and more — infiltrated the mice' organs, including the brain, as expected... Ross' team then ran the mice through a series of tests to examine their cognitive ability, beginning with an open-field test, in which researchers put a mouse in a chamber and allow it to explore at will for 90 minutes. Ordinarily, a mouse will hug the walls, naturally attempting to hide from potential predators. However, after microplastic exposure, the APOE4 mice — especially the male mice — tended to wander more in the middle of the chamber and spend time in open space, leaving themselves vulnerable to predators... The results are concerning enough to warrant further study into the cognitive decline caused by exposure to micro- and nanoplastics, which are among the most prominent environmental toxins to which people are routinely exposed... Ross is continuing to expand her research into the topic and encourages others to do so, in the hope of leading to better regulation of the toxins. Read more of this story at Slashdot.
Chimps consume alcohol equivalent of nearly 2 drinks a day
Science - Posted On:2025-09-19 17:15:00 Source: arstechnica
In 2014, University of California, Berkeley biologist Robert Dudley wrote a book called The Drunken Monkey: Why We Drink and Abuse Alcohol. His controversial "drunken monkey hypothesis" proposed that the human attraction to alcohol goes back about 18 million years, to the origin of the great apes, and that social communication and sharing food evolved to better identify the presence of fruit from a distance. At the time, skeptical scientists insisted that this was unlikely because chimpanzees and other primates just don't eat fermented fruit or nectar.
But reports of primates doing just that have grown over the ensuing two decades. Dudley co-authored a new paper published in the journal Science Advances reporting the first measurements of the ethanol content of fruits favored by chimps in Ivory Coast and Uganda, finding that the chimps are consuming 14 grams of alcohol every day, the equivalent of a standard alcoholic drink in the US. After adjusting for the chimps' lower body mass, the authors concluded the chimps are consuming nearly two drinks per day.
Earlier this year, we reported that researchers had caught wild chimpanzees on camera engaging in what appears to be sharing fermented African breadfruit with measurable alcoholic content. That observational data was the first evidence of the sharing of alcoholic foods among nonhuman great apes in the wild. They recorded 10 instances of selective fruit sharing among 17 chimps, with the animals exhibiting a marked preference for riper fruit. Between April and July 2022, the authors measured the alcohol content of the fruit with a handy portable breathalyzer and found almost all of the fallen fruit (90 percent) contained some ethanol, with the ripest containing the highest levels—the equivalent of 0.61 percent ABV (alcohol by volume).
Despite congressional threat, National Academies releases new climate report
Science - Posted On:2025-09-19 15:45:00 Source: arstechnica
Earlier this year, the Environmental Protection Agency announced that it was going to reject the work it had done back in 2009, when it first determined that greenhouse gas emissions posed a threat to the US public. While it laid out a number of reasons for revisiting its earlier work, one of those focused on the science: The EPA's original decision was over 15 years old, and it claimed our understanding of climate change had itself changed since then.
The National Academies of Science (NAS) decided that at least one aspect of that was probably right: Our understanding of the climate has changed in the last 15 years. So, it asked a group of scientists to do a quick update of our understanding of greenhouse gases, completed before public comment was closed on the EPA's plan. That report is now out, and the NAS's conclusion is clear: The EPA was right in 2009, and everything we've learned since has only made it more right.
The EPA's endangerment finding already had a long history by the time it was completed during the Obama administration. In it, the EPA concluded that greenhouse gases pose a risk to the US and its citizens, both directly through health impacts and indirectly through economic damages. Under the Clean Air Act, that finding enabled regulation of greenhouse gas emissions and formed the foundation of plans to reduce those originating from transportation and electrical generation. All of those plans have been held up in court or abandoned before coming into effect.
Meet the 2025 Ig Nobel Prize winners
Science - Posted On:2025-09-18 19:00:00 Source: arstechnica
Does alcohol enhance one's foreign language fluency? Do West African lizards have a preferred pizza topping? And can painting cows with zebra stripes help repel biting flies? These and other unusual research questions were honored tonight in a virtual ceremony to announce the 2025 recipients of the annual Ig Nobel Prizes. Yes, it's that time of year again, when the serious and the silly converge—for science.
Established in 1991, the Ig Nobels are a good-natured parody of the Nobel Prizes; they honor "achievements that first make people laugh and then make them think." The unapologetically campy awards ceremony features miniature operas, scientific demos, and the 24/7 lectures whereby experts must explain their work twice: once in 24 seconds and the second in just seven words.
Acceptance speeches are limited to 60 seconds. And as the motto implies, the research being honored might seem ridiculous at first glance, but that doesn't mean it's devoid of scientific merit. In the weeks following the ceremony, the winners will also give free public talks, which will be posted on the Improbable Research website.
Some dogs can classify their toys by function
Science - Posted On:2025-09-18 12:30:00 Source: arstechnica
Certain dogs can not only memorize the names of objects like their favorite toys, but they can also extend those labels to entirely new objects with a similar function, regardless of whether or not they are similar in appearance, according to a new paper published in the journal Current Biology. It's a cognitively advanced ability known as "label extension," and for animals to acquire it usually involves years of intensive training in captivity. But the dogs in this new study developed the ability to classify their toys by function with no formal training, merely by playing naturally with their owners.
Co-author Claudia Fugazza of Eötvös Loránd University in Budapest, Hungary, likens this ability to a person calling a hammer and a rock by the same name, or a child understanding that "cup" can describe a mug, a glass, or a tumbler, because they serve the same function. “The rock and the hammer look physically different, but they can be used for the same function," she said. "So now it turns out that these dogs can do the same.”
Fugazza and her Hungarian colleagues have been studying canine behavior and cognition for several years. For instance, in 2023, we reported on the group's experiments on how dogs interpret gestures, such as pointing at a specific object. A dog will interpret the gesture as a directional cue, unlike a human toddler, who will more likely focus on the object itself. It's called spatial bias, and the team concluded that the phenomenon arises from a combination of how dogs see (visual acuity) and how they think, with "smarter" dog breeds prioritizing an object's appearance as much as its location. This suggests the smarter dogs' information processing is more similar to that of humans.
Trump’s Golden Dome will cost 10 to 100 times more than the Manhattan Project
Science - Posted On:2025-09-18 12:30:00 Source: arstechnica
One thing that's evident about President Donald Trump's proposal for the Golden Dome missile defense shield is that designing, deploying, and sustaining it will cost a lot of money, at least several hundred billion dollars, over the course of several decades.
Beyond that, it's really anyone's guess. That doesn't sit well with some lawmakers, but the Republican-controlled Congress committed $25 billion in July as a down payment for new missile-defense technologies.
The White House stated in May that Golden Dome will cost $175 billion over three years, but a new study from a center-right think tank concludes that it is simply not enough to develop the kind of multi-layer shield Trump described in a January executive order. It's also clear that it will take longer than three years to implement the full spectrum of defense capability envisioned for Golden Dome.
Right-wing political violence is more frequent, deadly than left-wing violence
Science - Posted On:2025-09-18 11:15:01 Source: arstechnica
After the Sept. 10, 2025, assassination of conservative political activist Charlie Kirk, President Donald Trump claimed that radical leftist groups foment political violence in the US, and “they should be put in jail.”
“The radical left causes tremendous violence,” he said, asserting that “they seem to do it in a bigger way” than groups on the right.
Top presidential adviser Stephen Miller also weighed in after Kirk’s killing, saying that left-wing political organizations constitute “a vast domestic terror movement.”
Color-Changing Organogel Stretches 46 Times Its Size and Self-Heals
science - Posted On:2025-09-18 03:15:00 Source: slashdot
alternative_right shares a report from Phys.org: Scientists from Taiwan have developed a new material that can stretch up to 4,600% of its original length before breaking. Even if it does break, gently pressing the pieces together at room temperature allows it to heal, fully restoring its shape and stretchability within 10 minutes. The sticky and stretchy polyurethane (PU) organogels were designed by combining covalently linked cellulose nanocrystals (CNCs) and modified mechanically interlocked molecules (MIMs) that act as artificial molecular muscles. The muscles make the gel sensitive to external forces such as stretching or heat, where its color changes from orange to blue based on whether the material is at rest or stimulated. Thanks to these unique properties, the gels hold great promise for next-generation technologies -- from flexible electronic skins and soft robots to anti-counterfeiting solutions. The findings have been published in the journal Advanced Functional Materials. Read more of this story at Slashdot.
You can hold on to your butts thanks to DNA that evolved in fish
Science - Posted On:2025-09-17 19:00:01 Source: arstechnica
Evolution has adapted the digits of mammals for an enormous range of uses, from our opposable thumbs to the spindly digits that support bat wings to the robust bones that support the hoofs of horses. But how we got digits in the first place hasn't been entirely clear. The fish that limbed vertebrates evolved from don't have obvious digit equivalents, and the most common types of fish just have a large collection of rays supporting their fins.
Despite this uncertainty, we have identified some genes that seem to be essential for both digit formation and the development of rays in the fins of fish, suggesting that there are parallels between the two. But a new study suggests that these parallels are a bit of an accident, and digits come by re-deploying a genetic network that controls a completely different process: the formation of the cloaca, a single organ that handles all of the fish's excretion.
One of the key regulators of limb development is a set of genes called homeobox proteins, which attach to DNA and regulate the activity of nearby genes. In animals, many of these homeobox, or hox genes, are formed into clusters. Mammals have four clusters of hox genes, each of which encodes roughly 10 individual homeobox proteins. The cluster helps to organize where the hox genes are active, with the genes at one end of the cluster being active at the front of an embryo, and those at the other end active at the tail.